Journal Papers
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Y. Shimojo*, D. Tsuruta, T. Ozawa, T. Kono:
In silico evaluation based on tissue optics for picosecond laser treatment of pigmented lesions.
Journal of Japan Society for Laser Surgery and Medicine, in press. [in Japanese]
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G. Takeda*, Y. Shimojo*, T. Ozawa, T. Nishimura:
Spatial distribution of light-melanosome interaction dependent on irradiation fluence and spot size for short-pulsed laser skin treatment: A phantom study.
Lasers in Medical Science, in press.
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Y. Shimojo*, Y. Morizane, T. Sonokawa, J. Usuda, T. Nishimura*:
Optical characteristics of human lung cancer for photodynamic therapy with measured absorption and reduced scattering coefficients.
Journal of Biomedical Optics, 30, 048001 (2025).
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J. Jiracheewee, Y. Shimojo, T. Nishimura*:
Persistent homology-based optical properties of microscopic turbid media for realistic light propagation analysis.
Biomedical Optics Express, 16, 1651-1665 (2025).
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Y. Shimojo*, T. Nishimura, D. Tsuruta, T. Ozawa, T. Kono:
In silico evaluation of nanosecond laser treatment of pigmented lesions based on skin optical properties using a model of melanosome disruption threshold fluence.
Lasers in Surgery and Medicine, 57, 130-140 (2025).
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H. Fukuhara*, T. Nishimura, Y. Shimojo, K. Inoue:
Comparison of fluorescence intensity of protoporphyrin IX as observed on the screen of different cystoscopic systems.
Photodiagnosis and Photodynamic Therapy, 51, 104425 (2025).
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[H. Watabe, Y. Shimojo*], A. Shingu, H. Ito, H. Fukuhara, M. Miyake, K. Inoue, K. Fujimoto, T. Nishimura*:
Measurement of tissue optical properties in the 400–700 nm range to assess light penetration depths for laser treatment of upper tract urothelial carcinomas.
Journal of Biomedical Optics, 29, 125001 (2024).
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Y. Shimojo*, T. Nishimura*, D. Tsuruta, T. Ozawa:
Ultralow radiant exposure of a short-pulsed laser to disrupt melanosomes with localized thermal damage through a turbid medium.
Scientific Reports, 14, 20112 (2024).
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Y. Shimojo*, R. Teranishi, T. Nishimura, K. Kuwada, T. Goya, K. Morii, D. Tsuruta, T. Ozawa:
Antimicrobial photodynamic therapy using an organic light-emitting diode.
Journal of Japan Society for Laser Surgery and Medicine, 45, 153-160 (2024). [in Japanese]
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R. Teranishi, T. Ozawa*, B. Katayama, Y. Shimojo, N. Ito, K. Awazu, D. Tsuruta:
Effect of photodynamic therapy with 5-aminolevulinic acid and EDTA-2Na against mixed infection of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.
Photodermatology, Photoimmunology & Photomedicine, 40, e12959 (2024).
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Y. Shimojo*, T. Nishimura, D. Tsuruta, T. Ozawa, H.H.L. Chan, T. Kono:
Wavelength-dependent threshold fluences for melanosome disruption to evaluate the treatment of pigmented lesions with 532-, 730-, 755-, 785-, and 1064-nm picosecond lasers.
Lasers in Surgery and Medicine, 56, 404-418 (2024).
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H. Imanishi, T. Nishimura*, Y. Shimojo, K. Awazu:
Deep learning based depth map estimation of protoporphyrin IX in turbid media using dual wavelength excitation fluorescence.
Biomedical Optics Express, 14, 5254-5266 (2023).
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Y. Shimojo*, K. Sudo, T. Nishimura*, T. Ozawa, D. Tsuruta, K. Awazu:
Transient simulation of laser ablation based on Monte Carlo light transport with dynamic optical properties model.
Scientific Reports, 13, 11898 (2023).
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Y. Takai*, T. Nishimura*, Y. Shimojo, K. Awazu:
Artificial neural network-based determination of denoised optical properties in double integrating spheres measurement.
Journal of Innovative Optical Health Sciences, 16, 2350012, (2023).
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Y. Miyoshi*, T. Nishimura*, Y. Shimojo, K. Okayama, K. Awazu:
Endoscopic image-guided laser treatment system based on fiber bundle laser steering.
Scientific Reports, 13, 2921 (2023).
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Y. Shimojo*, T. Nishimura*, T. Ozawa, D. Tsuruta, K. Awazu:
Nonlinear absorption-based analysis of energy deposition in melanosomes for 532-nm short-pulsed laser skin treatment.
Lasers in Surgery and Medicine, 55, 305-315 (2023).
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T. Nishimura*, T. Suzuki, Y. Shimojo, R. Teranishi, T. Ozawa, D. Tsuruta, K. Awazu:
Mathematical modelling for antimicrobial photodynamic therapy mediated by 5-aminolaevulinic acid: an in vitro study.
Photodiagnosis and Photodynamic Therapy, 40, 103116 (2022).
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K. Sudo*, Y. Shimojo, T. Nishimura*, K. Awazu:
Three-dimensional transient simulation of CO2 laser tissue vaporization and experimental evaluation with a hydrogel phantom.
Journal of Innovative Optical Health Sciences, 15, 2250016 (2022). [Selected as Feturead Article 2022]
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Y. Shimojo*, T. Nishimura*, K. Awazu:
Photothermal effect induced by contact laser vaporization of porcine prostate tissue using XCAVATOR fiber.
Journal of Japan Society for Laser Surgery and Medicine, 42, 219-227 (2022). [in Japanese]
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Y. Shimojo*, T. Nishimura*, H. Hazama, N. Ito, K. Awazu:
Incident fluence analysis for 755-nm picosecond laser treatment of pigmented skin lesions based on threshold fluences for melanosome disruption.
Lasers in Surgery and Medicine, 53, 1096-1104 (2021).
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T. Nishimura*, Y. Takai, Y. Shimojo, H. Hazama, N. Ito, K. Awazu:
Determination of optical properties in double integrating sphere measurement by artificial neural network based method.
Optical Review, 28, 42-47 (2021).
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Y. Shimojo*, T. Nishimura*, H. Hazama, T. Ozawa, K. Awazu:
Measurement of absorption and reduced scattering coefficients in Asian human epidermis, dermis, and subcutaneous fat tissues in the 400- to 1100-nm wavelength range for optical penetration depth and energy deposition analysis.
Journal of Biomedical Optics, 25, 045002 (2020).
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Y. Shimojo*, T. Nishimura, H. Hazama, N. Ito, K. Awazu:
Picosecond laser-induced photothermal skin damage evaluation by computational clinical trial.
Laser Therapy, 29, 61-72 (2020).
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T. Nishimura*, Y. Shimojo, K. Awazu:
Computer-aided regulatory science for laser medicine.
Journal of Japan Society for Laser Surgery and Medicine, 41, 37-43 (2020). [in Japanese]
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T. Nishimura*, Y. Shimojo, H. Hazama, K. Awazu:
A method of computational clinical trial of a nanosecond pulsed laser skin treatment device by numerical simulation of phototermal damage.
Journal of Japan Society for Laser Surgery and Medicine, 40, 301-308 (2020). [in Japanese]
Proceedings
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T. Kikuchi, K. Watanabe, Y. Shimojo, H. Kawamura, E. Kinoshita, L. Ito, T. Ozawa:
Establishment of a novel and highly effective hair growth theory enabled by hair follicle stem cells.
IFSCC Magazine, 27, 165-169 (2023).
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Y. Shimojo, T. Nishimura, K. Awazu:
Quantitative evaluation of light distribution in skin tissue for short-pulsed laser treatment using Monte Carlo simulation combined with nonlinear absorption model of melanin.
Proceedings of SPIE, 12377 (2023).
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Y. Shimojo, T. Nishimura:
Incident fluence model based on tissue optical properties and threshold fluence for melanosome disruption for 755-nm picosecond laser treatment of benign pigmented lesions.
Lasers in Surgery and Medicine, 54(S34), S19 (2022).
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Y. Takai, Y. Shimojo, T. Nishimura, K. Awazu:
Artificial neural network based method to estimate optical properties in biological tissues for noise reduction.
Proceedings of Biophotonics Congress: Biomedical Optics 2022, JM3A.3 (2022).
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Y. Shimojo, T. Nishimura, K. Awazu:
Two-level model of melanin absorption in picosecond laser skin treatment.
Proceedings of SPIE, 11958 (2022).
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Y. Shimojo, T. Nishimura, H. Hazama, K. Awazu:
Experimental analysis of morphological change in melanin for multiscale modeling of picosecond laser skin treatment.
Proceedings of SPIE, 11640 (2021).
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Y. Shimojo, T. Nishimura, H. Hazama, T. Ozawa, K. Awazu:
Computational evaluation of ethnic differences in photothermal damage induced by laser skin treatments.
Proceedings of Biophotonics Congress: Biomedical Optics 2020, JTu3A.1 (2020).
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Y. Shimojo, T. Nishimura, H.Hazama, N. Ito, K. Awazu:
In silico evaluation of thermal skin damage caused by picosecond laser irradiation.
Proceedings of Biophotonics Congress: Optics in the Life Sciences Congress 2019, DS1A.7 (2019).
Others
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西村隆宏, 下条裕:
皮膚レーザー治療に対するin silico評価.
光学, 53, 148-153 (2024).
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菊地哲宏, 渡邉絋介, 下条裕, 伊藤廉, 小澤俊幸:
幹細胞に着目した新規アプローチによる育毛成分の探索.
Fragrance Journal, 51, 22-27 (2023).
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下条裕:
ピコ秒レーザーを用いたコンピュテーショナルレーザー治療の開発.
生産と技術, 75, 42-44 (2023).
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下条裕:
医療・医用レーザーデバイスを迅速に臨床応用するためのTranslational Research.
Laborify (2019).